S4
All-Wheel Drive · Automatic (S8) · Compact Cars
- MPG combined
- 24
- City / highway
- 20 / 29
- Engine
- 3.0L 6-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $3,400
- Tailpipe CO₂
- 377 g/mi

The Audi S4 has been sold in the US from 2000 to 2025, in 24 model years covered here. The 2025 line-up has 1 trim with 24 MPG combined.
All-Wheel Drive · Automatic (S8) · Compact Cars
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.