S5
All-Wheel Drive · Automatic (AM-S7) · Subcompact Cars
- MPG combined
- 21
- City / highway
- 18 / 28
- Engine
- 3.0L 6-cyl supercharged
- Fuel
- Premium
- Annual fuel cost
- $3,900
- Tailpipe CO₂
- 413 g/mi

The Audi S5 has been sold in the US from 2008 to 2027, in 20 model years covered here. The 2027 line-up has 1 trim with 23 MPG combined.
All-Wheel Drive · Automatic (AM-S7) · Subcompact Cars
All-Wheel Drive · Manual 6-spd · Subcompact Cars
All-Wheel Drive · Automatic (AM-S7) · Subcompact Cars
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.