ES 350
Front-Wheel Drive · Automatic (S6) · Midsize Cars
- MPG combined
- 22
- City / highway
- 19 / 27
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 404 g/mi

The Lexus ES has been sold in the US from 2000 to 2026, in 27 model years covered here. The 2026 line-up has 6 trims with 272–307 miles of EPA range and 44–46 MPG combined.
Front-Wheel Drive · Automatic (S6) · Midsize Cars
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.