GS 300 4WD
4-Wheel or All-Wheel Drive · Automatic (S6) · Midsize Cars
- MPG combined
- 21
- City / highway
- 19 / 25
- Engine
- 3.0L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,900
- Tailpipe CO₂
- 423 g/mi

The Lexus GS has been sold in the US from 2000 to 2020, in 20 model years covered here. The 2020 line-up has 4 trims with 19–23 MPG combined.
4-Wheel or All-Wheel Drive · Automatic (S6) · Midsize Cars
Rear-Wheel Drive · Automatic (S6) · Midsize Cars
Rear-Wheel Drive · Automatic (S6) · Midsize Cars
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.