IS 300
Rear-Wheel Drive · Manual 5-spd · Compact Cars
- MPG combined
- 18
- City / highway
- 16 / 23
- Engine
- 3.0L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $4,550
- Tailpipe CO₂
- 494 g/mi

The Lexus IS has been sold in the US from 2001 to 2026, in 26 model years covered here. The 2026 line-up has 2 trims with 22 MPG combined.
Rear-Wheel Drive · Manual 5-spd · Compact Cars
Rear-Wheel Drive · Automatic (S5) · Compact Cars
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.