E
World Of EVEditorial

Lexus RX

Plug-in hybridHybridGasSmall SUV

The Lexus RX has been sold in the US from 2000 to 2026, in 27 model years covered here. The 2026 line-up has 4 trims with 24–36 MPG combined.

Model years

2006 RX trims (6)

RX 400h 2WD

Hybrid

Front-Wheel Drive · Automatic (variable gear ratios) · Sport Utility Vehicle - 2WD

MPG combined
27
City / highway
28 / 25
Engine
3.3L 6-cyl
Fuel
Regular
Annual fuel cost
$2,500
Tailpipe CO₂
329 g/mi

RX 400h 4WD

Hybrid

4-Wheel or All-Wheel Drive · Automatic (variable gear ratios) · Sport Utility Vehicle - 4WD

MPG combined
26
City / highway
27 / 25
Engine
3.3L 6-cyl
Fuel
Regular
Annual fuel cost
$2,600
Tailpipe CO₂
342 g/mi

RX 330 2WD

Gas

Front-Wheel Drive · Automatic 5-spd · Sport Utility Vehicle - 2WD

MPG combined
20
City / highway
17 / 23
Engine
3.3L 6-cyl
Fuel
Premium
Annual fuel cost
$4,100
Tailpipe CO₂
444 g/mi

RX 330 2WD

Gas

Front-Wheel Drive · Automatic (S5) · Sport Utility Vehicle - 2WD

MPG combined
19
City / highway
17 / 23
Engine
3.3L 6-cyl
Fuel
Premium
Annual fuel cost
$4,350
Tailpipe CO₂
468 g/mi

RX 330 4WD

Gas

4-Wheel or All-Wheel Drive · Automatic 5-spd · Sport Utility Vehicle - 4WD

MPG combined
19
City / highway
16 / 22
Engine
3.3L 6-cyl
Fuel
Premium
Annual fuel cost
$4,350
Tailpipe CO₂
468 g/mi

RX 330 4WD

Gas

4-Wheel or All-Wheel Drive · Automatic (S5) · Sport Utility Vehicle - 4WD

MPG combined
18
City / highway
16 / 22
Engine
3.3L 6-cyl
Fuel
Premium
Annual fuel cost
$4,550
Tailpipe CO₂
494 g/mi

Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.