E
World Of EVEditorial

Lexus RX

Plug-in hybridHybridGasSmall SUV

The Lexus RX has been sold in the US from 2000 to 2026, in 27 model years covered here. The 2026 line-up has 4 trims with 24–36 MPG combined.

Model years

2008 RX trims (6)

RX 400h 2WD

Hybrid

Front-Wheel Drive · Automatic (variable gear ratios) · Sport Utility Vehicle - 2WD

MPG combined
25
City / highway
27 / 24
Engine
3.3L 6-cyl
Fuel
Premium
Annual fuel cost
$3,300
Tailpipe CO₂
355 g/mi

RX 400h 4WD

Hybrid

4-Wheel or All-Wheel Drive · Automatic (variable gear ratios) · Sport Utility Vehicle - 4WD

MPG combined
25
City / highway
26 / 24
Engine
3.3L 6-cyl
Fuel
Premium
Annual fuel cost
$3,300
Tailpipe CO₂
355 g/mi

RX 350 2WD

Gas

Front-Wheel Drive · Automatic 5-spd · Sport Utility Vehicle - 2WD

MPG combined
20
City / highway
18 / 23
Engine
3.5L 6-cyl
Fuel
Premium
Annual fuel cost
$4,100
Tailpipe CO₂
444 g/mi

RX 350 2WD

Gas

Front-Wheel Drive · Automatic (S5) · Sport Utility Vehicle - 2WD

MPG combined
20
City / highway
18 / 23
Engine
3.5L 6-cyl
Fuel
Premium
Annual fuel cost
$4,100
Tailpipe CO₂
444 g/mi

RX 350 4WD

Gas

4-Wheel or All-Wheel Drive · Automatic 5-spd · Sport Utility Vehicle - 4WD

MPG combined
19
City / highway
17 / 22
Engine
3.5L 6-cyl
Fuel
Premium
Annual fuel cost
$4,350
Tailpipe CO₂
468 g/mi

RX 350 4WD

Gas

4-Wheel or All-Wheel Drive · Automatic (S5) · Sport Utility Vehicle - 4WD

MPG combined
19
City / highway
17 / 22
Engine
3.5L 6-cyl
Fuel
Premium
Annual fuel cost
$4,350
Tailpipe CO₂
468 g/mi

Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.