RX 450h
Front-Wheel Drive · Automatic (AV-S6) · Small Sport Utility Vehicle 2WD
- MPG combined
- 29
- City / highway
- 31 / 28
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $2,850
- Tailpipe CO₂
- 301 g/mi

The Lexus RX has been sold in the US from 2000 to 2026, in 27 model years covered here. The 2026 line-up has 4 trims with 24–36 MPG combined.
Front-Wheel Drive · Automatic (AV-S6) · Small Sport Utility Vehicle 2WD
All-Wheel Drive · Automatic (AV-S6) · Small Sport Utility Vehicle 4WD
Front-Wheel Drive · Automatic (S6) · Small Sport Utility Vehicle 2WD
All-Wheel Drive · Automatic (S6) · Small Sport Utility Vehicle 4WD
All-Wheel Drive · Automatic (S8) · Small Sport Utility Vehicle 4WD
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.