S400 Hybrid
Rear-Wheel Drive · Automatic 7-spd · Large Cars
- MPG combined
- 21
- City / highway
- 19 / 25
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,900
- Tailpipe CO₂
- 423 g/mi
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World Of EVEditorial
Mercedes-Benz S-Class
The Mercedes-Benz S-Class has been sold in the US from 2000 to 2027, in 28 model years covered here. The 2027 line-up has 4 trims with 14–23 MPG combined.
Model years
2012 S-Class trims (6)
S550
Rear-Wheel Drive · Automatic 7-spd · Large Cars
- MPG combined
- 19
- City / highway
- 15 / 25
- Engine
- 4.7L 8-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $4,350
- Tailpipe CO₂
- 468 g/mi
S550 4matic
4-Wheel Drive · Automatic 7-spd · Large Cars
- MPG combined
- 18
- City / highway
- 15 / 24
- Engine
- 4.7L 8-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $4,550
- Tailpipe CO₂
- 494 g/mi
S600
Rear-Wheel Drive · Automatic 5-spd · Large Cars
- MPG combined
- 14
- City / highway
- 12 / 19
- Engine
- 5.5L 12-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $5,850
- Tailpipe CO₂
- 635 g/mi
S63 AMG
Rear-Wheel Drive · Automatic 7-spd · Large Cars
- MPG combined
- 18
- City / highway
- 15 / 23
- Engine
- 5.5L 8-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $4,550
- Tailpipe CO₂
- 494 g/mi
S65 AMG
Rear-Wheel Drive · Automatic 5-spd · Large Cars
- MPG combined
- 15
- City / highway
- 12 / 19
- Engine
- 6.0L 12-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $5,500
- Tailpipe CO₂
- 592 g/mi
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.