E
World Of EVEditorial

Mercedes-Benz S-Class

Plug-in hybridHybridGasLarge Cars

The Mercedes-Benz S-Class has been sold in the US from 2000 to 2027, in 28 model years covered here. The 2027 line-up has 4 trims with 14–23 MPG combined.

Model years

2025 S-Class trims (6)

AMG S63 E Performance

Plug-in hybrid

All-Wheel Drive · Automatic 9-spd · Midsize Cars

Electric range
16 mi
Total range
390 mi
On electricity
49 MPGe
On gas
18 MPG
Engine
4.0L 8-cyl turbo
Motor
140 and 150 kW AC PMSM
Annual fuel cost
$4,550
Tailpipe CO₂
305 g/mi

S580e 4matic

Plug-in hybrid

All-Wheel Drive · Automatic 9-spd · Large Cars

Electric range
48 mi
Total range
470 mi
On electricity
63 MPGe
On gas
23 MPG
Engine
3.0L 6-cyl turbo
Motor
110 kW AC PMSM
Annual fuel cost
$3,550
Tailpipe CO₂
106 g/mi

S500 4matic

Hybrid

All-Wheel Drive · Automatic 9-spd · Large Cars

MPG combined
24
City / highway
21 / 31
Engine
3.0L 6-cyl turbo supercharged
Fuel
Premium
Annual fuel cost
$3,400
Tailpipe CO₂
364 g/mi

S580 4matic

Hybrid

All-Wheel Drive · Automatic 9-spd · Large Cars

MPG combined
20
City / highway
17 / 25
Engine
4.0L 8-cyl turbo
Fuel
Premium
Annual fuel cost
$4,100
Tailpipe CO₂
448 g/mi

S580 4matic Maybach

Hybrid

All-Wheel Drive · Automatic 9-spd · Large Cars

MPG combined
20
City / highway
16 / 27
Engine
4.0L 8-cyl turbo
Fuel
Premium
Annual fuel cost
$4,100
Tailpipe CO₂
451 g/mi

Maybach S680 4matic

Gas

All-Wheel Drive · Automatic 9-spd · Large Cars

MPG combined
15
City / highway
12 / 20
Engine
6.0L 12-cyl turbo
Fuel
Premium
Annual fuel cost
$5,500
Tailpipe CO₂
603 g/mi

Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.