S500 4matic
All-Wheel Drive · Automatic 9-spd · Large Cars
- MPG combined
- 23
- City / highway
- 20 / 29
- Engine
- 3.0L 6-cyl turbo supercharged
- Fuel
- Premium
- Annual fuel cost
- $3,550
- Tailpipe CO₂
- 380 g/mi
E
World Of EVEditorial
Mercedes-Benz S-Class
The Mercedes-Benz S-Class has been sold in the US from 2000 to 2027, in 28 model years covered here. The 2027 line-up has 4 trims with 14–23 MPG combined.
Model years
2026 S-Class trims (4)
S580 4matic
All-Wheel Drive · Automatic 9-spd · Large Cars
- MPG combined
- 20
- City / highway
- 17 / 27
- Engine
- 4.0L 8-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $4,100
- Tailpipe CO₂
- 438 g/mi
S580 4matic Maybach
All-Wheel Drive · Automatic 9-spd · Large Cars
- MPG combined
- 20
- City / highway
- 16 / 27
- Engine
- 4.0L 8-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $4,100
- Tailpipe CO₂
- 451 g/mi
Maybach S680 4matic
All-Wheel Drive · Automatic 9-spd · Large Cars
- MPG combined
- 15
- City / highway
- 12 / 20
- Engine
- 6.0L 12-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $5,500
- Tailpipe CO₂
- 603 g/mi
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.