E
World Of EVEditorial

Mercedes-Benz E-Class

Plug-in hybridHybridDieselGasMidsize Cars

The Mercedes-Benz E-Class has been sold in the US from 2000 to 2027, in 28 model years covered here. The 2027 line-up has 4 trims with 25–28 MPG combined.

Model years

2000 E-Class trims (7)

E320

Gas

Rear-Wheel Drive · Automatic 5-spd · Midsize Cars

MPG combined
21
City / highway
18 / 27
Engine
3.2L 6-cyl
Fuel
Premium
Annual fuel cost
$3,900
Tailpipe CO₂
423 g/mi

E320 (Wagon)

Gas

Rear-Wheel Drive · Automatic 5-spd · Midsize Station Wagons

MPG combined
20
City / highway
18 / 25
Engine
3.2L 6-cyl
Fuel
Premium
Annual fuel cost
$4,100
Tailpipe CO₂
444 g/mi

E320 4Matic

Gas

4-Wheel or All-Wheel Drive · Automatic 5-spd · Midsize Cars

MPG combined
21
City / highway
18 / 25
Engine
3.2L 6-cyl
Fuel
Premium
Annual fuel cost
$3,900
Tailpipe CO₂
423 g/mi

E320 4Matic (Wagon)

Gas

4-Wheel or All-Wheel Drive · Automatic 5-spd · Midsize Station Wagons

MPG combined
20
City / highway
17 / 24
Engine
3.2L 6-cyl
Fuel
Premium
Annual fuel cost
$4,100
Tailpipe CO₂
444 g/mi

E430

Gas

Rear-Wheel Drive · Automatic 5-spd · Midsize Cars

MPG combined
18
City / highway
16 / 22
Engine
4.3L 8-cyl
Fuel
Premium
Annual fuel cost
$4,550
Tailpipe CO₂
494 g/mi

E430 4Matic

Gas

4-Wheel or All-Wheel Drive · Automatic 5-spd · Midsize Cars

MPG combined
18
City / highway
16 / 21
Engine
4.3L 8-cyl
Fuel
Premium
Annual fuel cost
$4,550
Tailpipe CO₂
494 g/mi

E55 AMG

Gas

Rear-Wheel Drive · Automatic 5-spd · Midsize Cars

MPG combined
17
City / highway
15 / 21
Engine
5.5L 8-cyl
Fuel
Premium
Annual fuel cost
$4,850
Tailpipe CO₂
523 g/mi

Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.