E
World Of EVEditorial

Mercedes-Benz E-Class

Plug-in hybridHybridDieselGasMidsize Cars

The Mercedes-Benz E-Class has been sold in the US from 2000 to 2027, in 28 model years covered here. The 2027 line-up has 4 trims with 25–28 MPG combined.

Model years

2016 E-Class trims (16)

AMG E63 4matic

Gas

4-Wheel Drive · Automatic 7-spd · Midsize Cars

MPG combined
19
City / highway
16 / 23
Engine
5.5L 8-cyl turbo
Fuel
Premium
Annual fuel cost
$4,350
Tailpipe CO₂
475 g/mi

AMG E63 S 4matic

Gas

4-Wheel Drive · Automatic 7-spd · Midsize Cars

MPG combined
18
City / highway
15 / 22
Engine
5.5L 8-cyl turbo
Fuel
Premium
Annual fuel cost
$4,550
Tailpipe CO₂
498 g/mi

AMG E63 S 4matic (wagon)

Gas

4-Wheel Drive · Automatic 7-spd · Midsize Station Wagons

MPG combined
18
City / highway
16 / 21
Engine
5.5L 8-cyl turbo
Fuel
Premium
Annual fuel cost
$4,550
Tailpipe CO₂
497 g/mi

E350

Gas

Rear-Wheel Drive · Automatic 7-spd · Midsize Cars

MPG combined
23
City / highway
20 / 29
Engine
3.5L 6-cyl
Fuel
Premium or E85
Annual fuel cost
$3,550
Tailpipe CO₂
377 g/mi

E350

Gas

Rear-Wheel Drive · Automatic 7-spd · Midsize Cars

MPG combined
23
City / highway
20 / 28
Engine
3.5L 6-cyl
Fuel
Premium
Annual fuel cost
$3,550
Tailpipe CO₂
379 g/mi

E350 4matic

Gas

4-Wheel Drive · Automatic 7-spd · Midsize Cars

MPG combined
23
City / highway
20 / 27
Engine
3.5L 6-cyl
Fuel
Premium or E85
Annual fuel cost
$3,550
Tailpipe CO₂
384 g/mi

E350 4matic

Gas

4-Wheel Drive · Automatic 7-spd · Midsize Cars

MPG combined
23
City / highway
20 / 27
Engine
3.5L 6-cyl
Fuel
Premium
Annual fuel cost
$3,550
Tailpipe CO₂
384 g/mi

E350 4matic (wagon)

Gas

4-Wheel Drive · Automatic 7-spd · Midsize Station Wagons

MPG combined
22
City / highway
20 / 26
Engine
3.5L 6-cyl
Fuel
Premium
Annual fuel cost
$3,750
Tailpipe CO₂
396 g/mi

E400

Gas

Rear-Wheel Drive · Automatic 7-spd · Midsize Cars

MPG combined
23
City / highway
20 / 29
Engine
3.0L 6-cyl turbo
Fuel
Premium
Annual fuel cost
$3,550
Tailpipe CO₂
378 g/mi

E400 4matic

Gas

4-Wheel Drive · Automatic 7-spd · Midsize Cars

MPG combined
22
City / highway
20 / 27
Engine
3.0L 6-cyl turbo
Fuel
Premium
Annual fuel cost
$3,750
Tailpipe CO₂
395 g/mi

E400 4matic Coupe

Gas

4-Wheel Drive · Automatic 7-spd · Subcompact Cars

MPG combined
23
City / highway
20 / 28
Engine
3.0L 6-cyl turbo
Fuel
Premium
Annual fuel cost
$3,550
Tailpipe CO₂
386 g/mi

E400 Convertible

Gas

Rear-Wheel Drive · Automatic 7-spd · Subcompact Cars

MPG combined
23
City / highway
20 / 29
Engine
3.0L 6-cyl turbo
Fuel
Premium
Annual fuel cost
$3,550
Tailpipe CO₂
377 g/mi

E400 Coupe

Gas

Rear-Wheel Drive · Automatic 7-spd · Subcompact Cars

MPG combined
23
City / highway
20 / 29
Engine
3.0L 6-cyl turbo
Fuel
Premium
Annual fuel cost
$3,550
Tailpipe CO₂
377 g/mi

E550 4matic

Gas

4-Wheel Drive · Automatic 7-spd · Midsize Cars

MPG combined
21
City / highway
18 / 24
Engine
4.7L 8-cyl turbo
Fuel
Premium
Annual fuel cost
$3,900
Tailpipe CO₂
435 g/mi

E550 Convertible

Gas

Rear-Wheel Drive · Automatic 7-spd · Subcompact Cars

MPG combined
20
City / highway
17 / 25
Engine
4.7L 8-cyl turbo
Fuel
Premium
Annual fuel cost
$4,100
Tailpipe CO₂
443 g/mi

E550 Coupe

Gas

Rear-Wheel Drive · Automatic 7-spd · Subcompact Cars

MPG combined
21
City / highway
18 / 26
Engine
4.7L 8-cyl turbo
Fuel
Premium
Annual fuel cost
$3,900
Tailpipe CO₂
430 g/mi

Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.