E
World Of EVEditorial

Mercedes-Benz E-Class

Plug-in hybridHybridDieselGasMidsize Cars

The Mercedes-Benz E-Class has been sold in the US from 2000 to 2027, in 28 model years covered here. The 2027 line-up has 4 trims with 25–28 MPG combined.

Model years

2005 E-Class trims (10)

E320 Cdi

Diesel

Rear-Wheel Drive · Automatic 5-spd · Midsize Cars

MPG combined
27
City / highway
23 / 33
Engine
3.2L 6-cyl turbo
Fuel
Diesel
Annual fuel cost
$3,550
Tailpipe CO₂
377 g/mi

E320

Gas

Rear-Wheel Drive · Automatic 5-spd · Midsize Cars

MPG combined
20
City / highway
18 / 26
Engine
3.2L 6-cyl
Fuel
Premium
Annual fuel cost
$4,100
Tailpipe CO₂
444 g/mi

E320 (Wagon)

Gas

Rear-Wheel Drive · Automatic 5-spd · Midsize Station Wagons

MPG combined
20
City / highway
17 / 25
Engine
3.2L 6-cyl
Fuel
Premium
Annual fuel cost
$4,100
Tailpipe CO₂
444 g/mi

E320 4matic

Gas

4-Wheel or All-Wheel Drive · Automatic 5-spd · Midsize Cars

MPG combined
19
City / highway
17 / 23
Engine
3.2L 6-cyl
Fuel
Premium
Annual fuel cost
$4,350
Tailpipe CO₂
468 g/mi

E320 4matic (Wagon)

Gas

4-Wheel or All-Wheel Drive · Automatic 5-spd · Midsize Station Wagons

MPG combined
19
City / highway
16 / 22
Engine
3.2L 6-cyl
Fuel
Premium
Annual fuel cost
$4,350
Tailpipe CO₂
468 g/mi

E500

Gas

Rear-Wheel Drive · Automatic 7-spd · Midsize Cars

MPG combined
18
City / highway
15 / 23
Engine
5.0L 8-cyl
Fuel
Premium
Annual fuel cost
$4,550
Tailpipe CO₂
494 g/mi

E500 4matic

Gas

4-Wheel or All-Wheel Drive · Automatic 5-spd · Midsize Cars

MPG combined
16
City / highway
14 / 19
Engine
5.0L 8-cyl
Fuel
Premium
Annual fuel cost
$5,150
Tailpipe CO₂
555 g/mi

E500 4matic (Wagon)

Gas

4-Wheel or All-Wheel Drive · Automatic 5-spd · Midsize Station Wagons

MPG combined
16
City / highway
14 / 18
Engine
5.0L 8-cyl
Fuel
Premium
Annual fuel cost
$5,150
Tailpipe CO₂
555 g/mi

E55 AMG

Gas

Rear-Wheel Drive · Automatic (S5) · Midsize Cars

MPG combined
15
City / highway
13 / 19
Engine
5.4L 8-cyl supercharged
Fuel
Premium
Annual fuel cost
$5,500
Tailpipe CO₂
592 g/mi

E55 AMG (Wagon)

Gas

Rear-Wheel Drive · Automatic (S5) · Midsize Station Wagons

MPG combined
15
City / highway
13 / 19
Engine
5.4L 8-cyl supercharged
Fuel
Premium
Annual fuel cost
$5,500
Tailpipe CO₂
592 g/mi

Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.