E350
Rear-Wheel Drive · Automatic 7-spd · Midsize Cars
- MPG combined
- 23
- City / highway
- 20 / 30
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,550
- Tailpipe CO₂
- 386 g/mi
E
World Of EVEditorial
Mercedes-Benz E-Class
The Mercedes-Benz E-Class has been sold in the US from 2000 to 2027, in 28 model years covered here. The 2027 line-up has 4 trims with 25–28 MPG combined.
Model years
2012 E-Class trims (14)
E350 4matic
4-Wheel Drive · Automatic 7-spd · Midsize Cars
- MPG combined
- 22
- City / highway
- 19 / 28
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 404 g/mi
E350 4matic (wagon)
4-Wheel Drive · Automatic 7-spd · Midsize Station Wagons
- MPG combined
- 22
- City / highway
- 19 / 27
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 404 g/mi
E350 4matic Coupe
4-Wheel Drive · Automatic 7-spd · Subcompact Cars
- MPG combined
- 22
- City / highway
- 19 / 27
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 404 g/mi
E350 4matic Coupe
4-Wheel Drive · Automatic 7-spd · Subcompact Cars
- MPG combined
- 22
- City / highway
- 19 / 27
- Engine
- 3.5L 6-cyl
- Fuel
- Premium or E85
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 404 g/mi
E350 Convertible
Rear-Wheel Drive · Automatic 7-spd · Subcompact Cars
- MPG combined
- 22
- City / highway
- 19 / 28
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 404 g/mi
E350 Convertible
Rear-Wheel Drive · Automatic 7-spd · Subcompact Cars
- MPG combined
- 22
- City / highway
- 19 / 28
- Engine
- 3.5L 6-cyl
- Fuel
- Premium or E85
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 404 g/mi
E350 Coupe
Rear-Wheel Drive · Automatic 7-spd · Subcompact Cars
- MPG combined
- 22
- City / highway
- 19 / 28
- Engine
- 3.5L 6-cyl
- Fuel
- Premium
- Annual fuel cost
- $3,750
- Tailpipe CO₂
- 404 g/mi
E350 Coupe
Rear-Wheel Drive · Automatic 7-spd · Subcompact Cars
- MPG combined
- 23
- City / highway
- 20 / 28
- Engine
- 3.5L 6-cyl
- Fuel
- Premium or E85
- Annual fuel cost
- $3,550
- Tailpipe CO₂
- 386 g/mi
E550 4matic
4-Wheel Drive · Automatic 7-spd · Midsize Cars
- MPG combined
- 20
- City / highway
- 16 / 26
- Engine
- 4.7L 8-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $4,100
- Tailpipe CO₂
- 444 g/mi
E550 Convertible
Rear-Wheel Drive · Automatic 7-spd · Subcompact Cars
- MPG combined
- 19
- City / highway
- 16 / 25
- Engine
- 4.7L 8-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $4,350
- Tailpipe CO₂
- 468 g/mi
E550 Coupe
Rear-Wheel Drive · Automatic 7-spd · Subcompact Cars
- MPG combined
- 21
- City / highway
- 17 / 27
- Engine
- 4.7L 8-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $3,900
- Tailpipe CO₂
- 423 g/mi
E63 AMG
Rear-Wheel Drive · Automatic 7-spd · Midsize Cars
- MPG combined
- 19
- City / highway
- 16 / 24
- Engine
- 5.5L 8-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $4,350
- Tailpipe CO₂
- 468 g/mi
E63 AMG (wagon)
Rear-Wheel Drive · Automatic 7-spd · Midsize Station Wagons
- MPG combined
- 18
- City / highway
- 15 / 23
- Engine
- 5.5L 8-cyl turbo
- Fuel
- Premium
- Annual fuel cost
- $4,550
- Tailpipe CO₂
- 494 g/mi
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.