AMG E53 Hybrid 4matic Plus
All-Wheel Drive · Automatic 9-spd · Midsize Cars
- Electric range
- 44 mi
- Total range
- 420 mi
- On electricity
- 60 MPGe
- On gas
- 24 MPG
- Engine
- 3.0L 6-cyl turbo
- Motor
- 120 kW AC PMSM
- Annual fuel cost
- $3,400
- Tailpipe CO₂
- 115 g/mi

The Mercedes-Benz E-Class has been sold in the US from 2000 to 2027, in 28 model years covered here. The 2027 line-up has 4 trims with 25–28 MPG combined.
All-Wheel Drive · Automatic 9-spd · Midsize Cars
All-Wheel Drive · Automatic 9-spd · Midsize Station Wagons
Rear-Wheel Drive · Automatic 9-spd · Midsize Cars
All-Wheel Drive · Automatic 9-spd · Midsize Cars
All-Wheel Drive · Automatic 9-spd · Midsize Cars
All-Wheel Drive · Automatic 9-spd · Midsize Station Wagons
Source: U.S. EPA / DOE fueleconomy.gov. Annual fuel cost is the EPA estimate for 15,000 miles a year at national average fuel and electricity prices.